Competing with the incubation centers of the world's leading universities, İTÜ Çekirdek was chosen as the 2nd best in Europe and the third best in the world by UBI Global and achieved great success for our country. Models suitable for entrepreneurship ecosystem are designed and implemented at İTÜ Çekirdek Early Stage Incubation Center, and the business model methods and contents used in the world's leading universities and entrepreneurship centers are adapted to local conditions and needs. Prof. Dr. Mehmet Karaca, who is İTÜ ARI Teknokent Chairman of the Board and Rector of ITU, shared his knowledge and experiences.